We analyzed the DNA content of 40 gastric carcinomas using the flowcytometry. In 19 of 40 cases, the DNA content was measured separately in the superficial and deeper portions of a tumor. All were advanced gastric carcinomas.
Twenty
seven tumor(67.5%) were aneuploid. There was no relationship between the ploidy and the clinical parameters, such as, age and sex of patients, histologic type and differentiation of a tumor, depth of tumor invasion, lymph
node
metastasis and tumor stage. Intratumoral differences in DNA ploidy were observed in the tumor specimen, because cases exist where
subpopulation with DNA aneuploidy are detected only at limited sites within the same tumor.
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